Robust and annotation-free analysis of alternative splicing across diverse cell types in mice

Robust and annotation-free analysis of alternative splicing across diverse cell types in mice

Although alternative splicing is a fundamental and pervasive aspect of gene expression in higher eukaryotes, it is often omitted from single-cell studies due to quantification challenges inherent to commonly used short-read sequencing technologies. Here, we undertake the analysis of alternative spli...

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Bibliographic Details
Main Authors: Gonzalo Benegas, Jonathan Fischer, Yun S Song
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
alternative splicing
single-cell RNA-seq
primary motor cortex neurons
Tabula Muris
splicing factors
Online Access:https://elifesciences.org/articles/73520

Internet

https://elifesciences.org/articles/73520

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