OTUB1-mediated deubiquitination of FOXM1 up-regulates ECT-2 to promote tumor progression in renal cell carcinoma

OTUB1-mediated deubiquitination of FOXM1 up-regulates ECT-2 to promote tumor progression in renal cell carcinoma

Abstract Background OTUB1 (ovarian tumor domain protease domain-containing ubiquitin aldehyde-binding proteins)-mediated deubiquitination of FOXM1 (Forkhead box M1) participates in carcinogenesis of various tumors. We aim to investigate the effect and mechanism of OTUB1/FOXM1 on RCC (renal cell carc...

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Bibliographic Details
Main Authors: Kai Zhou, Haixing Mai, Song Zheng, Weizhong Cai, Xu Yang, Zhenlin Chen, Bin Zhan
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cell & Bioscience
Subjects:
OTUB1
FOXM1
ECT-2
Renal cell carcinoma
Progression
Online Access:http://link.springer.com/article/10.1186/s13578-020-00408-0

Internet

http://link.springer.com/article/10.1186/s13578-020-00408-0

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