Peripheral nerves in the tibial subchondral bone: the role of pain and homeostasis in osteoarthritis

Peripheral nerves in the tibial subchondral bone: the role of pain and homeostasis in osteoarthritis

Osteoarthritis (OA) is a highly prevalent degenerative joint disorder characterized by joint pain and physical disability. Aberrant subchondral bone induces pathological changes and is a major source of pain in OA. In the subchondral bone, which is highly innervated, nerves have dual roles in pain s...

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Bibliographic Details
Main Authors: Qi Sun, Gen Li, Di Liu, Wenqing Xie, Wenfeng Xiao, Yusheng Li, Ming Cai
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2022-07-01
Series:Bone & Joint Research
Subjects:
osteoarthritis
subchondral bone
peripheral innervation
pain
homeostasis
peripheral nerves
tibial subchondral bone
nerves
neurones
bone homeostasis
sympathetic nervous systems
bone cells
osteoarthritis (oa)
degenerative joint disorder
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.117.BJR-2021-0355.R1

Internet

https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.117.BJR-2021-0355.R1

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