Impact of glucocorticoids on the incidence of lupus-related major organ damage: a systematic literature review and meta-regression analysis of longitudinal observational studies

Objective In systemic lupus erythematosus (SLE), disease activity and glucocorticoid (GC) exposure are known to contribute to irreversible organ damage. We aimed to examine the association between GC exposure and organ damage occurrence.Methods We conducted a literature search (PubMed (Medline), Emb...

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Main Authors: Ronald F van Vollenhoven, Laurent Arnaud, Marta Mosca, Nathalie Costedoat-Chalumeau, Elisabet Svenungsson, Daniel J Wallace, Judith A James, Kenneth Kalunian, Susan Manzi, Michelle A Petri, Jill Buyon, Rosalind Ramsey-Goldman, Ian N Bruce, Guillermo Ruiz-Irastorza, Ellen M Ginzler, Manuel Francisco Ugarte-Gil, Bernardo A Pons-Estel, Juanita Romero-Diaz, Sang-Cheol Bae, Anisur Rahman, Paul R Fortin, Dafna D Gladman, Andreas Jönsen, Murat Inanc, Diane L Kamen, Søren Jacobsen, Jorge Sanchez-Guerrero, Évelyne Vinet, Murray Urowitz, David Isenberg, Sasha Bernatsky, John Reynolds, Eric Morand, Vernon Farewell, Claudia Elera-Fitzcarrald, Cristina Reátegui-Sokolova, Alexandre Voskuyl, Anca D Askanase, John Hanly, Anselm Mak, Sung Sam Lim, Christine Peschken, Graciela S. Alarcon, Joanna Leong, Bhushan Dharmadhikari, Nien Yee Kow, Cinthia Aranow, Mary Ann Dooley, Mike Cheung
Format: Article
Language:English
Published: BMJ Publishing Group 2021-05-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/8/1/e000590.full