Growth arrest‐specific protein 2 (GAS2) interacts with CXCR4 to promote T‐cell leukemogenesis partially via c‐MYC

Growth arrest‐specific protein 2 (GAS2) interacts with CXCR4 to promote T‐cell leukemogenesis partially via c‐MYC

Although growth arrest‐specific protein 2 (GAS2) promotes the growth of T‐cell acute lymphoblastic leukemia (T‐ALL) cells in culture, the effect of GAS2 on T‐cell leukemogenesis has not been studied, and the mechanism remains unclear. In the present study, xenograft studies showed that GAS2 silencin...

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Bibliographic Details
Main Authors: Wenjuan Ma, Yan Wan, Jianxiang Zhang, Jianan Yao, Yifei Wang, Jinchang Lu, Hong Liu, Xiaorui Huang, Xiuyan Zhang, Haixia Zhou, Yulong He, Depei Wu, Jianrong Wang, Yun Zhao
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Molecular Oncology
Subjects:
c‐MYC
CXCR4
GAS2
hematopoiesis
leukemogenesis
T‐ALL
Online Access:https://doi.org/10.1002/1878-0261.13306

Internet

https://doi.org/10.1002/1878-0261.13306

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