A Moonlighting microRNA: Mechanism(s) of miR-122-Mediated Viral RNA Accumulation

A Moonlighting microRNA: Mechanism(s) of miR-122-Mediated Viral RNA Accumulation

Hepatitis C virus (HCV) is a positive-sense RNA virus that interacts with a human-liver-specific microRNA, termed miR-122. miR-122 binds to two sites in the 5' untranslated region (UTR) of the viral genome, and this interaction promotes<b><i> </i></b>HCV RNA accumulation...

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Bibliographic Details
Main Authors: Jasmin Chahal, Luca FR Gebert, Hin Hark Gan, Kristin C Gunsalus, Ian J MacRae, Selena M Sagan
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Proceedings
Subjects:
Hepatitis C virus
Argonaute
miR-122
microRNA
Internal Ribosomal Entry Site
pyrophosphatase
Online Access:https://www.mdpi.com/2504-3900/50/1/131

Internet

https://www.mdpi.com/2504-3900/50/1/131

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