OLA1 promotes colorectal cancer tumorigenesis by activation of HIF1α/CA9 axis

Abstract Background Obg-like ATPase 1 (OLA1) is a highly conserved GTPase, which was over expressed in a variety of malignant tumors, but its role in colorectal cancer (CRC) was poorly studied. Patients and methods Three public CRC gene databases were applied for OLA1 mRNA expression detection. The...

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Bibliographic Details
Main Authors: Yue Liu, Xiang-Xing Kong, Jin-Jie He, Yan-Bo Xu, Jian-Kun Zhang, Lu-Yang Zou, Ke-Feng Ding, Dong Xu
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-09508-1