Adjuvant hepatic arterial infusion pump chemotherapy and resection versus resection alone in patients with low-risk resectable colorectal liver metastases – the multicenter randomized controlled PUMP trial

Abstract Background Recurrences are reported in 70% of all patients after resection of colorectal liver metastases (CRLM), in which half are confined to the liver. Adjuvant hepatic arterial infusion pump (HAIP) chemotherapy aims to reduce the risk of intrahepatic recurrence. A large retrospective pr...

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Main Authors: F. E. Buisman, M. Y. V. Homs, D. J. Grünhagen, W. F. Filipe, R. J. Bennink, M. G. H. Besselink, I. H. M. Borel Rinkes, R. C. G. Bruijnen, A. Cercek, M. I. D’Angelica, O. M. van Delden, M. L. Donswijk, L. van Doorn, P. G. Doornebosch, J. Emmering, J. I. Erdmann, N. S. IJzerman, C. Grootscholten, J. Hagendoorn, N. E. Kemeny, T. P. Kingham, E. G. Klompenhouwer, N. F. M. Kok, S. Koolen, K. F. D. Kuhlmann, M. C. Kuiper, M. G. E. Lam, R. H. J. Mathijssen, A. Moelker, E. Oomen-de Hoop, C. J. A. Punt, W. W. te Riele, J. M. L. Roodhart, R. J. Swijnenburg, W. Prevoo, P. J. Tanis, M. Vermaas, M. W. J. Versleijen, F. P. Veuger, M. J. Weterman, C. Verhoef, B. Groot Koerkamp
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Cancer
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Online Access:http://link.springer.com/article/10.1186/s12885-019-5515-6