Cingulate circuits are associated with escalation of heroin use and naloxone-induced increases in heroin self-administration

Cingulate circuits are associated with escalation of heroin use and naloxone-induced increases in heroin self-administration

Opioid use disorder (OUD) is defined as a compulsion to seek and take opioids, loss of control over intake and the development of a negative emotional state when access to opioids is denied. Using functional magnetic resonance imaging (fMRI) data in a rat model of OUD, we demonstrate that the escala...

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Bibliographic Details
Main Authors: Scarlata MJ, Keeley RJ, Carmack SA, Tsai P-J, Vendruscolo JCM, Lu H, Koob GF, Vendruscolo LF, Stein EA
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Addiction Neuroscience
Subjects:
Opioid dependence
Opioid addiction
fMRI
Cingulate
Circuit
Online Access:http://www.sciencedirect.com/science/article/pii/S277239252100002X

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http://www.sciencedirect.com/science/article/pii/S277239252100002X

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