Association of T Cell–Derived Inflammatory Cytokines With Acute Kidney Injury and Mortality After Cardiac Surgery

Introduction: Animal models of renal ischemia-reperfusion injury (IRI) demonstrate that interferon (IFN)-γ producing T-helper (Th)-1 cells worsen acute kidney injury (AKI), whereas interleukin (IL)-4– and IL-13–producing Th2 cells lead to repair. We tested the association of these cytokines with AKI...

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Bibliographic Details
Main Authors: Dennis G. Moledina, Sherry G. Mansour, Yaqi Jia, Wassim Obeid, Heather Thiessen-Philbrook, Jay L. Koyner, Eric McArthur, Amit X. Garg, F. Perry Wilson, Michael G. Shlipak, Steven G. Coca, Chirag R. Parikh
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Kidney International Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024919314792