Occurrence of multipolar mitoses and association with Aurora-A/-B kinases and p53 mutations in aneuploid esophageal carcinoma cells

<p>Abstract</p> <p>Background</p> <p>Aurora kinases and loss of p53 function are implicated in the carcinogenesis of aneuploid esophageal cancers. Their association with occurrence of multipolar mitoses in the two main histotypes of aneuploid esophageal squamous cell ca...

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Bibliographic Details
Main Authors: Münch Claudia, Herz Corinna, Fichter Christiane D, Opitz Oliver G, Werner Martin, Lassmann Silke
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/12/13