Chinese medicinal plant Polygonum cuspidatum ameliorates silicosis via suppressing the Wnt/β-catenin pathway

Chinese medicinal plant Polygonum cuspidatum ameliorates silicosis via suppressing the Wnt/β-catenin pathway

Polygonum cuspidatum (PC) extract has effect on silica-induced pulmonary fibrosis. This study aimed to explore the anti-pulmonary-fibrosis effects and mechanism of PC. Sprague–Dawley rat model was constructed by inhalation of silicon dioxide suspension through tracheal intubation method. And histopa...

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Bibliographic Details
Main Authors: Jia Yangmin, Wang Anlong, Liu Libin, Wang Huaichong, Li Guohui, Zhang Fengwei
Format: Article
Language:English
Published: De Gruyter 2022-12-01
Series:Open Chemistry
Subjects:
polygonum cuspidatum
silicosis
pulmonary fibrosis
wnt/β-catenin signaling pathway
fibroblast
Online Access:https://doi.org/10.1515/chem-2022-0266

Internet

https://doi.org/10.1515/chem-2022-0266

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