Structural Studies Reveal the Role of Helix 68 in the Elongation Step of Protein Biosynthesis

Structural Studies Reveal the Role of Helix 68 in the Elongation Step of Protein Biosynthesis

ABSTRACT The ribosome, a multicomponent assembly consisting of RNA and proteins, is a pivotal macromolecular machine that translates the genetic code into proteins. The large ribosomal subunit rRNA helix 68 (H68) is a key element in the protein synthesis process, as it coordinates the coupled moveme...

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Bibliographic Details
Main Authors: Giuseppe Cimicata, Gil Fridkin, Tanaya Bose, Zohar Eyal, Yehuda Halfon, Elinor Breiner-Goldstein, Tara Fox, Ella Zimmerman, Anat Bashan, Natalia de Val, Alexander Wlodawer, Ada Yonath
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:mBio
Subjects:
ribosome
H68
translation
protein synthesis
PNA
antisense
Online Access:https://journals.asm.org/doi/10.1128/mbio.00306-22

Internet

https://journals.asm.org/doi/10.1128/mbio.00306-22

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