Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment

<p>Abstract</p> <p>The tumor microenvironment consists of tumor, immune, stromal, and inflammatory cells which produce cytokines, growth factors, and adhesion molecules that promote tumor progression and metastasis. Of particular interest in this setting is interleukin-1 (IL-1), a...

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Bibliographic Details
Main Authors: Varghese Sheelu, Lewis Anne M, Xu Hui, Alexander H Richard
Format: Article
Language:English
Published: BMC 2006-11-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/4/1/48