Selective reduction of post-selection CD8 thymocyte proliferation in IL-15Rα deficient mice.

Selective reduction of post-selection CD8 thymocyte proliferation in IL-15Rα deficient mice.

Peripheral CD8(+) T cells are defective in both IL-15 and IL-15Rα knock-out (KO) mice; however, whether IL-15/IL-15Rα deficiency has a similar effect on CD8 single-positive (SP) thymocytes remains unclear. In this study, we investigated whether the absence of IL-15 transpresentation in IL-15Rα KO mi...

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Bibliographic Details
Main Authors: Kai-Ping N Chow, Jian-Tai Qiu, Jam-Mou Lee, Shuo-Lun Hsu, Shan-Che Yang, Ning-Ning Wu, Wei Huang, Tzong-Shoon Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3308975?pdf=render

Internet

http://europepmc.org/articles/PMC3308975?pdf=render

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