Vimentin Levels and Serine 71 Phosphorylation in the Control of Cell-Matrix Adhesions, Migration Speed, and Shape of Transformed Human Fibroblasts

Vimentin Levels and Serine 71 Phosphorylation in the Control of Cell-Matrix Adhesions, Migration Speed, and Shape of Transformed Human Fibroblasts

Metastasizing tumor cells show increased expression of the intermediate filament (IF) protein vimentin, which has been used to diagnose invasive tumors for decades. Recent observations indicate that vimentin is not only a passive marker for carcinoma, but may also induce tumor cell invasion. To clar...

Full description

Bibliographic Details
Main Authors: Emmanuel Terriac, Giovanna Coceano, Zahra Mavajian, Tijmen A. G. Hageman, Andreas F. Christ, Ilaria Testa, Franziska Lautenschläger, Annica K. B. Gad
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Cells
Subjects:
focal adhesions
vimentin
cell migration
total internal reflection (TIRF) microscopy
stimulated emission depletion (STED) microscopy
Online Access:http://www.mdpi.com/2073-4409/6/1/2

Internet

http://www.mdpi.com/2073-4409/6/1/2

Similar Items