Asymmetric clustering of centrosomes defines the early evolution of tetraploid cells

Tetraploidy has long been of interest to both cell and cancer biologists, partly because of its documented role in tumorigenesis. A common model proposes that the extra centrosomes that are typically acquired during tetraploidization are responsible for driving tumorigenesis. However, tetraploid cel...

Полное описание

Библиографические подробности
Главные авторы: Nicolaas C Baudoin, Joshua M Nicholson, Kimberly Soto, Olga Martin, Jing Chen, Daniela Cimini
Формат: Статья
Язык:English
Опубликовано: eLife Sciences Publications Ltd 2020-04-01
Серии:eLife
Предметы:
Online-ссылка:https://elifesciences.org/articles/54565