Synthesis and Evaluation of 2,4-Disubstituted Quinazoline Derivatives with Potent Anti-Angiogenesis Activities

A series of 2,4-disubstituted quinazoline derivatives were designed and synthesized. The biological results showed that most of quinazoline derivatives exhibited potent antiproliferative activities against a panel of three tumor cell lines and a good inhibitory effect against the adhesion and migrat...

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Bibliographic Details
Main Authors: Guangjin Yu, Zeng Li, Liang Tang, Qiru Xiong
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/7/8916