PAM-repeat associations and spacer selection preferences in single and co-occurring CRISPR-Cas systems
Abstract Background The adaptive CRISPR-Cas immune system stores sequences from past invaders as spacers in CRISPR arrays and thereby provides direct evidence that links invaders to hosts. Mapping CRISPR spacers has revealed many aspects of CRISPR-Cas biology, including target requirements such as t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-09-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-021-02495-9 |