Immunologic and Protective Properties of Subunit- vs. Whole Toxoid-Derived Anti-Botulinum Equine Antitoxin

Botulism is a paralytic disease caused by botulinum neurotoxins (BoNTs). Equine antitoxin is currently the standard therapy for botulism in human. The preparation of equine antitoxin relies on the immunization of horses with botulinum toxoid, which suffers from low yield and safety limitations. The...

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Main Authors: Alon Ben David, Ada Barnea, Amram Torgeman, Eran Diamant, Eyal Dor, Arieh Schwartz, Osnat Rosen, Noa Caspi, Miki Saraf, Elad Lerer, Yaakov Adar, Edith Lupo, Einat Toister, Ran Zichel
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/9/1522