Redirecting pantoprazole as a metallo-beta-lactamase inhibitor in carbapenem-resistant Klebsiella pneumoniae

Redirecting pantoprazole as a metallo-beta-lactamase inhibitor in carbapenem-resistant Klebsiella pneumoniae

The development of resistance to carbapenems in Klebsiella pneumoniae due to the production of metallo-β-lactamases (MBLs) is a critical public health problem because carbapenems are the last-resort drugs used for treating severe infections of extended-spectrum β-lactamases (ESBLs) producing K. pneu...

Full description

Bibliographic Details
Main Authors: Wesam H. Abdulaal, Nabil A. Alhakamy, Amer H. Asseri, Mohamed F. Radwan, Tarek S. Ibrahim, Solomon Z. Okbazghi, Hisham A. Abbas, Basem Mansour, Aly A. Shoun, Wael A. H. Hegazy, Mahmoud Saad Abdel-Halim
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Pharmacology
Subjects:
Klebsiella pneumoniae
pantoprazole
carbapenems
metallo-β-lactamase inhibitor
healthcare
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1366459/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1366459/full

Similar Items