Intratumoral CXCR5+CD8+T associates with favorable clinical outcomes and immunogenic contexture in gastric cancer

The prognostic value of tumor infiltrating lymphocytes in gastric cancer remains controversial. Here the authors show a consistent association between higher density of intratumoral CXCR5+CD8+ T cells and longer overall survival in four different cohorts of patients with gastric cancer.

Bibliographic Details
Main Authors: Jieti Wang, Ruochen Li, Yifan Cao, Yun Gu, Hanji Fang, Yuchao Fei, Kunpeng Lv, Xudong He, Chao Lin, Hao Liu, Heng Zhang, He Li, Hongyong He, Jiejie Xu, Hua Huang
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23356-w