Mir-21 Suppression Promotes Mouse Hepatocarcinogenesis

Mir-21 Suppression Promotes Mouse Hepatocarcinogenesis

The microRNA 21 (miR-21) is upregulated in almost all known human cancers and is considered a highly potent oncogene and potential therapeutic target for cancer treatment. In the liver, miR-21 was reported to promote hepatic steatosis and inflammation, but whether miR-21 also drives hepatocarcinogen...

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Bibliographic Details
Main Authors: Marta Correia de Sousa, Nicolas Calo, Cyril Sobolewski, Monika Gjorgjieva, Sophie Clément, Christine Maeder, Dobrochna Dolicka, Margot Fournier, Laurent Vinet, Xavier Montet, Jean-François Dufour, Bostjan Humar, Francesco Negro, Christine Sempoux, Michelangelo Foti
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
microRNA 21
HCC
oncogenes
tumor suppressors
inflammation
fibrosis
Online Access:https://www.mdpi.com/2072-6694/13/19/4983

Internet

https://www.mdpi.com/2072-6694/13/19/4983

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