Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina

Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina

Abstract Adenylyl cyclase 6 (AC6) synthesizes second messenger cAMP in G protein-coupled receptor (GPCR) signaling. In cochlear hair cells, AC6 distribution relies on an adhesion GPCR, ADGRV1, which is associated with Usher syndrome (USH), a condition of combined hearing and vision loss. ADGRV1 is a...

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Bibliographic Details
Main Authors: Pranav Dinesh Mathur, Junhuang Zou, Grace Neiswanger, Daniel Zhu, Yong Wang, Ali A. Almishaal, Deepti Vashist, H. Kirk Hammond, Albert H. Park, Jun Yang
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34361-y

Internet

https://doi.org/10.1038/s41598-023-34361-y

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