Exploring the Relationship between Gut Microbiome Composition and Blood Indole-3-acetic Acid in Hemodialysis Patients

Exploring the Relationship between Gut Microbiome Composition and Blood Indole-3-acetic Acid in Hemodialysis Patients

Indole-3-acetic acid (IAA), a protein-bound uremic toxin resulting from gut microbiota-driven tryptophan metabolism, increases in hemodialysis (HD) patients. IAA may induce endothelial dysfunction, inflammation, and oxidative stress, elevating cardiovascular and cognitive risk in HD patients. Howeve...

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Bibliographic Details
Main Authors: Ping-Hsun Wu, Yu-Fang Tseng, Wangta Liu, Yun-Shiuan Chuang, Chi-Jung Tai, Chun-Wei Tung, Kean-Yee Lai, Mei-Chuan Kuo, Yi-Wen Chiu, Shang-Jyh Hwang, Wei-Chun Hung, Yi-Ting Lin
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomedicines
Subjects:
indole-3-acetic acid
microbiome
hemodialysis
end-stage kidney disease
Online Access:https://www.mdpi.com/2227-9059/12/1/148

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https://www.mdpi.com/2227-9059/12/1/148

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