An Evolutionary Conservation and Druggability Analysis of Enzymes Belonging to the Bacterial Shikimate Pathway

Enzymes belonging to the shikimate pathway have long been considered promising targets for antibacterial drugs because they have no counterpart in mammals and are essential for bacterial growth and virulence. However, despite decades of research, there are currently no clinically relevant antibacter...

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Bibliographic Details
Main Author: Rok Frlan
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/11/5/675