Liquiritin and Liquiritigenin Induce Melanogenesis via Enhancement of p38 and PKA Signaling Pathways

Liquiritin and Liquiritigenin Induce Melanogenesis via Enhancement of p38 and PKA Signaling Pathways

<b>Background:</b> Liquiritin (LQ) and its aglycone, liquiritigenin (LQG), are major flavonoids in licorice root (<i>Glycyrrhiza</i> spp.). Our preliminary screening identified LQ and LQG, which promote melanin synthesis in the melanoma cells. In this study, we investigated t...

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Bibliographic Details
Main Authors: Takuhiro Uto, Tomoe Ohta, Akihisa Yamashita, Shunsuke Fujii, Yukihiro Shoyama
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Medicines
Subjects:
licorice
liquiritigenin
liquiritin
melanin
tyrosinase
TRP-1/2
MITF
p38
PKA
Online Access:https://www.mdpi.com/2305-6320/6/2/68

Internet

https://www.mdpi.com/2305-6320/6/2/68

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