MethylMasteR: A Comparison and Customization of Methylation-Based Copy Number Variation Calling Software in Cancers Harboring Large Scale Chromosomal Deletions

MethylMasteR: A Comparison and Customization of Methylation-Based Copy Number Variation Calling Software in Cancers Harboring Large Scale Chromosomal Deletions

DNA methylation-based copy number variation (CNV) calling software offers the advantages of providing both genetic (copy-number) and epigenetic (methylation) state information from a single genomic library. This method is advantageous when looking at large-scale chromosomal rearrangements such as th...

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Bibliographic Details
Main Authors: Michael P. Mariani, Jennifer A. Chen, Ze Zhang, Steven C. Pike, Lucas A. Salas
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Bioinformatics
Subjects:
methylmaster
copy number variation
DNA methylation
kidney cancer
clear cell renal cell carcinoma
epigenetics
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2022.859828/full

Internet

https://www.frontiersin.org/articles/10.3389/fbinf.2022.859828/full

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