KPNA2 promotes osteosarcoma growth and metastasis in a c-Myc-dependent manner via the hedgehog /GLI1 signaling pathway

Despite recent advances, the poor outcomes in osteosarcoma suggest that novel therapeutic targets are needed. Karyopherin alpha 2 (KPNA2) has been identified as a novel oncogene in many cancers. However, the function of KPNA2 in osteosarcoma and its relative mechanisms remain unclear. Herein, we rep...

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Bibliographic Details
Main Authors: Sheng Zhou, Chao Zhuang, Ruiping Liu
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223002678