Coexistence of a novel SRBD1-ALK, ALK-CACNA1D double-fusion in a lung adenocarcinoma patient and response to alectinib: A case report

Coexistence of a novel SRBD1-ALK, ALK-CACNA1D double-fusion in a lung adenocarcinoma patient and response to alectinib: A case report

A Chinese male patient with advanced lung adenocarcinoma experienced disease progression one and a half years after receiving first-line immunochemotherapy. The second biopsy was performed and tissue immunohistochemistry revealed Anaplastic lymphoma kinase (ALK) expression in the cytoplasm of tumor...

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Bibliographic Details
Main Authors: Xiaohong Xie, Wenhui Guan, Wenting Huang, Juhong Jiang, Haiyi Deng, Yijia Li, Huixin Jiang, Ming Liu, Chengzhi Zhou
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
Anaplastic lymphoma kinase
Alectinib
S1 RNA binding domain 1
Calcium voltage-gated channel subunit alpha1 D
Non-small cell lung cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024004043

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http://www.sciencedirect.com/science/article/pii/S2405844024004043

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