Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice.

Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice.

Alzheimer's disease (AD) is heterogeneous and multifactorial neurological disorder; and the risk factors of AD still remain elusive. Recent studies have highlighted the role of vascular factors in promoting the progression of AD and have suggested that ischemic events increase the incidence of...

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Bibliographic Details
Main Authors: Lin Lu, Lan Guo, Esha Gauba, Jing Tian, Lu Wang, Neha Tandon, Malini Shankar, Simon J Beck, Yifeng Du, Heng Du
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4669173?pdf=render

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http://europepmc.org/articles/PMC4669173?pdf=render

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