Exploiting tertiary lymphoid structures gene signature to evaluate tumor microenvironment infiltration and immunotherapy response in colorectal cancer

Exploiting tertiary lymphoid structures gene signature to evaluate tumor microenvironment infiltration and immunotherapy response in colorectal cancer

BackgroundTertiary lymphoid structures (TLS) is a particular component of tumor microenvironment (TME). However, its biological mechanisms in colorectal cancer (CRC) have not yet been understood. We desired to reveal the TLS gene signature in CRC and evaluate its role in prognosis and immunotherapy...

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Bibliographic Details
Main Authors: Zhu Xu, Qin Wang, Yiyao Zhang, Xiaolan Li, Mei Wang, Yuhong Zhang, Yaxin Pei, Kezhen Li, Man Yang, Liping Luo, Chuan Wu, Weidong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Oncology
Subjects:
tertiary lymphoid structures
colorectal cancer
tumor microenvironment
prognostic
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1383096/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1383096/full

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