Optogenetic activation of the ventral tegmental area-hippocampal pathway facilitates rapid adaptation to changes in spatial goals

Summary: Animal adaptation to environmental goals to pursue rewards is modulated by dopamine. However, the role of dopamine in the hippocampus, involved in spatial navigation, remains unclear. Here, we studied dopaminergic inputs from the ventral tegmental area (VTA) to the hippocampus, focusing on...

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Bibliographic Details
Main Authors: Yuta Tamatsu, Hirotsugu Azechi, Riku Takahashi, Fumiya Sawatani, Kaoru Ide, Fumino Fujiyama, Susumu Takahashi
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223026135