DNase inhibits early biofilm formation in Pseudomonas aeruginosa- or Staphylococcus aureus-induced empyema models

DNase inhibits early biofilm formation in Pseudomonas aeruginosa- or Staphylococcus aureus-induced empyema models

Anti-infection strategies against pleural empyema include the use of antibiotics and drainage treatments, but bacterial eradication rates remain low. A major challenge is the formation of biofilms in the pleural cavity. DNase has antibiofilm efficacy in vitro, and intrapleural therapy with DNase is...

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Bibliographic Details
Main Authors: Wusheng Deng, Yanmei Lei, Xiujia Tang, Dingbin Li, Jinhua Liang, Jing Luo, Liuyuan Liu, Wenshu Zhang, Liumei Ye, Jinliang Kong, Ke Wang, Zhaoyan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
DNase
Pseudomonas aeruginosa
Staphylococcus aureus
pleural empyema
biofilm
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.917038/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.917038/full

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