The role of innate immunity in atherogenesis1

Lipid peroxidation is a common event in health and is greatly accelerated in pro-inflammatory settings such as hypercholesterolemia. Consequently, oxidation-specific epitopes are generated, which are pro-inflammatory and immunogenic, leading to both adaptive and innate responses. Because innate immu...

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Bibliographic Details
Main Authors: Karsten Hartvigsen, Meng-Yun Chou, Lotte F. Hansen, Peter X. Shaw, Sotirios Tsimikas, Christoph J. Binder, Joseph L. Witztum
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520306441