Enzymatic formation of prostamide F2α from anandamide involves a newly identified intermediate metabolite, prostamide H2

Prostaglandin F2α 1-ethanolamide (prostamide F2α) is a potent ocular hypotensive agent in animals and represents a new class of fatty acid amide compounds. Accumulated evidence indicated that anandamide, an endogenous bioactive ligand for cannabinoid receptors, may serve as a common substrate to pro...

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Bibliographic Details
Main Authors: Wu Yang, Jinsong Ni, David F. Woodward, Diane D-S. Tang-Liu, Kah-Hiing John Ling
Format: Article
Language:English
Published: Elsevier 2005-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520328637