Multi-omic analysis reveals dynamic changes of three-dimensional chromatin architecture during T cell differentiation
Abstract Cell differentiation results in widespread changes in transcriptional programs as well as multi-level remodeling of three-dimensional genome architecture. Nonetheless, few synthetically investigate the chromatin higher-order landscapes in different T helper (Th) cells. Using RNA-Seq, ATAC-S...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-07-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-05141-1 |