Design and Optimization of Omeprazole-Curcumin-Loaded Hydrogel Beads Coated with Chitosan for Treating Peptic Ulcers

Design and Optimization of Omeprazole-Curcumin-Loaded Hydrogel Beads Coated with Chitosan for Treating Peptic Ulcers

This study aimed to formulate a pharmaceutical dosage form containing omeprazole (OMP) and curcumin (CURC) to treat experimental peptic ulcers. OMP and CURC were preliminarily complexed with hydroxypropyl-β-cyclodextrin for enhancing their solubilization. After that, the combined complex (CURC/OMP)...

Full description

Bibliographic Details
Main Authors: Eman J. Heikal, Rashad M. Kaoud, Shadeed Gad, Hatem I. Mokhtar, Afaf A. Aldahish, Wafa Ali Alzlaiq, Sawsan A. Zaitone, Yasser M. Moustafa, Taha M. Hammady
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceuticals
Subjects:
omeprazole
curcumin
hydroxypropyl-β-cyclodextrin
chitosan-alginate hydrogel
ulcer
Online Access:https://www.mdpi.com/1424-8247/16/6/795

Internet

https://www.mdpi.com/1424-8247/16/6/795

Similar Items