Design and Optimization of Omeprazole-Curcumin-Loaded Hydrogel Beads Coated with Chitosan for Treating Peptic Ulcers

Design and Optimization of Omeprazole-Curcumin-Loaded Hydrogel Beads Coated with Chitosan for Treating Peptic Ulcers

This study aimed to formulate a pharmaceutical dosage form containing omeprazole (OMP) and curcumin (CURC) to treat experimental peptic ulcers. OMP and CURC were preliminarily complexed with hydroxypropyl-β-cyclodextrin for enhancing their solubilization. After that, the combined complex (CURC/OMP)...

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Bibliographic Details
Main Authors:	Eman J. Heikal, Rashad M. Kaoud, Shadeed Gad, Hatem I. Mokhtar, Afaf A. Aldahish, Wafa Ali Alzlaiq, Sawsan A. Zaitone, Yasser M. Moustafa, Taha M. Hammady
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Series:	Pharmaceuticals
Subjects:	omeprazole curcumin hydroxypropyl-β-cyclodextrin chitosan-alginate hydrogel ulcer
Online Access:	https://www.mdpi.com/1424-8247/16/6/795

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