Expression and prognostic value of PRDX family in colon adenocarcinoma by integrating comprehensive analysis and in vitro and in vivo validation

BackgroundThe peroxiredoxin family, a crucial regulator of redox reactions, is strongly associated with various tumorigenesis. However, the role of peroxiredoxin4 (PRDX4) in colon adenocarcinoma (COAD) remains poorly understood.MethodsMulticenter databases, including GEPIA, HPA, UALCAN, cBioPortal,...

Full description

Bibliographic Details
Main Authors: He Zhou, Lifa Li, Jia Chen, Songlin Hou, Tong Zhou, Yongfu Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1136738/full