The Co-occurrence of Chronic Hepatitis B and Fibrosis Is Associated With a Decrease in Hepatic Global DNA Methylation Levels in Patients With Non-alcoholic Fatty Liver Disease

The Co-occurrence of Chronic Hepatitis B and Fibrosis Is Associated With a Decrease in Hepatic Global DNA Methylation Levels in Patients With Non-alcoholic Fatty Liver Disease

Global DNA hypomethylation has been reported in patients with chronic hepatitis B (CHB) and non-alcoholic fatty-liver disease (NAFLD). However, the global DNA methylation profile of patients with concurrent NAFLD and CHB (NAFLD + CHB) is still unclear. We aimed to detect the hepatic global DNA methy...

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Bibliographic Details
Main Authors: FangYuan Li, Qian Ou, ZhiWei Lai, LiuZhen Pu, XingYi Chen, LiRong Wang, LiuQiao Sun, XiaoPing Liang, YaoYao Wang, Hang Xu, Jun Wei, Feng Wu, HuiLian Zhu, LiJun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Genetics
Subjects:
global DNA methylation
chronic hepatitis B
fibrosis
non-alcoholic fatty-liver disease
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.671552/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.671552/full

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