Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis (ORN) in Head and Neck Cancer Patients Treated With Pencil-Beam-Scanning Proton Therapy (PBSPT): A Retrospective, Case-Matched Cohort Study

Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis (ORN) in Head and Neck Cancer Patients Treated With Pencil-Beam-Scanning Proton Therapy (PBSPT): A Retrospective, Case-Matched Cohort Study

PurposeTo retrospectively investigate empirical relative biological effectiveness (RBE) for mandible osteoradionecrosis (ORN) in head and neck (H&N) cancer patients treated with pencil-beam-scanning proton therapy (PBSPT).MethodsWe included 1,266 H&N cancer patients, of which, 931 pa...

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Bibliographic Details
Main Authors: Yunze Yang, Olivia M. Muller, Satomi Shiraishi, Matthew Harper, Adam C. Amundson, William W. Wong, Lisa A. McGee, Jean-Claude M. Rwigema, Steven E. Schild, Martin Bues, Mirek Fatyga, Justin D. Anderson, Samir H. Patel, Robert L. Foote, Wei Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
relative biological effectiveness
mandibular osteoradionecrosis
linear energy transfer (LET)
pencil beam scanning proton therapy (PBSPT)
head and neck (H&N) cancer
volume modulated arc-therapy (VMAT)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.843175/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.843175/full

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