Immunosuppressive glycoproteins associate with breast tumor fibrosis and aggression

Tumors feature elevated sialoglycoprotein content. Sialoglycoproteins promote tumor progression and are linked to immune suppression via the sialic acid-Siglec axis. Understanding factors that increase sialoglycoprotein biosynthesis in tumors could identify approaches to improve patient response to...

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Bibliographic Details
Main Authors: Kevin James Metcalf, Mary-Kate Hayward, Eric Berens, Alastair J. Ironside, Connor Stashko, E. Shelley Hwang, Valerie M. Weaver
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Matrix Biology Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590028522000059