Immunosuppressive glycoproteins associate with breast tumor fibrosis and aggression

Immunosuppressive glycoproteins associate with breast tumor fibrosis and aggression

Tumors feature elevated sialoglycoprotein content. Sialoglycoproteins promote tumor progression and are linked to immune suppression via the sialic acid-Siglec axis. Understanding factors that increase sialoglycoprotein biosynthesis in tumors could identify approaches to improve patient response to...

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Bibliographic Details
Main Authors:	Kevin James Metcalf, Mary-Kate Hayward, Eric Berens, Alastair J. Ironside, Connor Stashko, E. Shelley Hwang, Valerie M. Weaver
Format:	Article
Language:	English
Published:	Elsevier 2022-06-01
Series:	Matrix Biology Plus
Subjects:	Sialic acid Sialoglycoproteins Siglec receptors Breast cancer Fibrosis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590028522000059

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