Endoplasmic Reticulum Stress and Dysregulated Autophagy in Human Pancreatic Beta Cells

Endoplasmic Reticulum Stress and Dysregulated Autophagy in Human Pancreatic Beta Cells

Pancreatic beta cell homeostasis is crucial for the synthesis and secretion of insulin; disruption of homeostasis causes diabetes, and is a treatment target. Adaptation to endoplasmic reticulum (ER) stress through the unfolded protein response (UPR) and adequate regulation of autophagy, which are cl...

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Bibliographic Details
Main Authors: Seoil Moon, Hye Seung Jung
Format: Article
Language:English
Published: Korean Diabetes Association 2022-07-01
Series:Diabetes & Metabolism Journal
Subjects:
autophagy
diabetes mellitus
endoplasmic reticulum stress
humans
insulin-secreting cells
insulin secretion
unfolded protein response
Online Access:http://e-dmj.org/upload/pdf/dmj-2022-0070.pdf

Internet

http://e-dmj.org/upload/pdf/dmj-2022-0070.pdf

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