Endoplasmic Reticulum Stress and Dysregulated Autophagy in Human Pancreatic Beta Cells
Pancreatic beta cell homeostasis is crucial for the synthesis and secretion of insulin; disruption of homeostasis causes diabetes, and is a treatment target. Adaptation to endoplasmic reticulum (ER) stress through the unfolded protein response (UPR) and adequate regulation of autophagy, which are cl...
Main Authors: | Seoil Moon, Hye Seung Jung |
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Format: | Article |
Language: | English |
Published: |
Korean Diabetes Association
2022-07-01
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Series: | Diabetes & Metabolism Journal |
Subjects: | |
Online Access: | http://e-dmj.org/upload/pdf/dmj-2022-0070.pdf |
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