Toxoplasma acyl-CoA synthetase TgACS3 is crucial to channel host fatty acids in lipid droplets and for parasite propagation

Toxoplasma acyl-CoA synthetase TgACS3 is crucial to channel host fatty acids in lipid droplets and for parasite propagation

Apicomplexa comprise important pathogenic parasitic protists that heavily depend on lipid acquisition to survive within their human host cells. Lipid synthesis relies on the incorporation of an essential combination of fatty acids (FAs) either generated by a metabolically adaptable de novo synthesis...

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Bibliographic Details
Main Authors: Sheena Dass, Serena Shunmugam, Sarah Charital, Samuel Duley, Christophe-Sébastien Arnold, Nicholas J. Katris, Pierre Cavaillès, Marie-France Cesbron-Delauw, Yoshiki Yamaryo-Botté, Cyrille Y. Botté
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Journal of Lipid Research
Subjects:
Toxoplasma gondii
apicomplexa
host-parasite metabolic interactions
Lipid metabolism
membrane biogenesis
fatty acid activation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227524001500

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http://www.sciencedirect.com/science/article/pii/S0022227524001500

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