A VLP library of C-terminally truncated Hepatitis B core proteins: correlation of RNA encapsidation with a Th1/Th2 switch in the immune responses of mice.

A VLP library of C-terminally truncated Hepatitis B core proteins: correlation of RNA encapsidation with a Th1/Th2 switch in the immune responses of mice.

An efficient pBR327- and Ptrp-based E. coli expression system was used to generate a large-scale library of virus like particles (VLP) formed by recombinant hepatitis B virus (HBV) core (HBc) protein derivatives. To construct the library, the gene of HBc protein of the genotype D/subtype ayw2 virus...

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Bibliographic Details
Main Authors: Irina Sominskaya, Dace Skrastina, Ivars Petrovskis, Andris Dishlers, Ieva Berza, Maria Mihailova, Juris Jansons, Inara Akopjana, Irina Stahovska, Dzidra Dreilina, Velta Ose, Paul Pumpens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24086668/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24086668/?tool=EBI

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