Naturally acquired antibodies against Plasmodium vivax pre-erythrocytic stage vaccine antigens inhibit sporozoite invasion of human hepatocytes in vitro

Naturally acquired antibodies against Plasmodium vivax pre-erythrocytic stage vaccine antigens inhibit sporozoite invasion of human hepatocytes in vitro

Abstract In Plasmodium vivax, the most studied vaccine antigens are aimed at blocking merozoite invasion of erythrocytes and disease development. Very few studies have evaluated pre-erythrocytic (PE) stage antigens. The P. vivax circumsporozoite protein (CSP), is considered the leading PE vaccine ca...

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Detaylı Bibliyografya
Asıl Yazarlar: Francis Babila Ntumngia, Surendra Kumar Kolli, Pradeep Annamalai Subramani, Samantha J. Barnes, Justin Nicholas, Madison M. Ogbondah, Brian B. Barnes, Nichole D. Salinas, Pongsakorn Thawornpan, Niraj H. Tolia, Patchanee Chootong, John H. Adams
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Nature Portfolio 2024-01-01
Seri Bilgileri:Scientific Reports
Online Erişim:https://doi.org/10.1038/s41598-024-51820-2

Internet

https://doi.org/10.1038/s41598-024-51820-2

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