Anti-fibrotic effect of decorin in peritoneal dialysis and PD-associated peritonitis

Background: Progressive peritoneal fibrosis is a common complication in patients on long-term peritoneal dialysis (PD). PD-associated peritonitis is a major exacerbating factor. We investigated the anti-fibrotic properties of decorin secreted by peritoneal mesothelial cells. Methods: Dialysate decor...

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Bibliographic Details
Main Authors: Na Jiang, Qing Zhang, Mel KM Chau, Ming S Yip, Sing Leung Lui, Stephanie Liu, Kent Man Chu, Hextan YS Ngan, Tak Mao Chan, Susan Yung
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420300360